To develop and use the technology for high-throughput structural and functional studies of proteins.

The Protein Structure Initiative Structural Genomics Knowledgebase (PSI SGKB) is designed to turn the products of the Protein Structure Initiative effort into knowledge that is important for understanding living systems and disease. The PSI SGKB is a key resource in the advancement of biology, biochemistry, functional genomics, pharmacology, bioinformatics, education and clinical medicine.