NYSGXRC

Centers

NIGMS supports the following research centers in its protein structure initiative. brief summaries of the centers are available below.

Large-Scale Centers

Joint Center For Structural Genomics

Principal Investigator: Ian Wilson, Scripps Research Institute

Participating Institutions:

The Scripps Research Institute,
The University Of California At San Diego,
The Burnham Institute,
Stanford Synchrotron Radiation Laboratory,
The Genomics Institute of the Novartis Research Foundation

Midwest Center For Structural Genomics

Principal Investigator: Andrzej Joachimiak, Argonne National Laboratory

Participating Institutions:

Argonne National Laboratory,
European Bioinformatics Institute,
University College London,
The University Of Toronto

New York Structural Genomix Research Consortium

Principal Investigator: Stephen K. Burley, SGX Pharmaceuticals Inc., San Diego, Calif.

Participating Institutions:

Sgx Pharmaceuaticals Inc.,
Albert Einstein College Of Medicine,
Brookhaven National Laboratory,
Case Western Reserve University,
University Of California, San Francisco

Northeast Structural Genomics Consortium

Principal Investigator: Gaetano Montelione, Rutgers University

Participating Institutions:

Columbia University,
Hauptman Woodward Medical Research Institute,
Ontario Cancer Institute At The University Of Toronto,
Pacific Northwest National Laboratories,
Rutgers University,
Robert Wood Johnson Medical School At The Umdnj,
Weill Medical School At Cornell University And Yale University

Specialized Centers

Accelerated Technologies Center For Gene To 3d Structure
Principal Investigator: Lance J. Stewart, Decode Biostructures
Participating Institutions:
- Decode Biostructures;
- The Scripps Research Institute;
- University Of Chicago;
- Lyncean Technologies, Inc.;
- Micronics, Inc.
Center For Eukaryotic Structural Genomics
Principal Investigator: John L. Markley, University Of Wisconsin, Madison
Participating Institutions:
- University Of Wisconsin, Madison;
- Medical College Of Wisconsin
Center For High-Throughput Structural Biology
Principal Investigator: George T. De Titta, Hauptman-Woodward Medical Research Institute
Participating Institutions:
- Hauptman-Woodward Medical Research Institute,
- University Of Rochester,
- Cornell University,
- Stanford Synchrotron Light Source,
- University Of Pittsburgh,
- University Of Washington At Seattle
- The University Of Toronto
Center For Structures Of Membrane Proteins
Principal Investigator: Robert M. Stroud, University Of California, San Francisco
Participating Institutions:
- University Of California, San Francisco;
- The Salk Institute;
- Advanced Light Source (als) Lawrence Berkeley National Laboratory;
- University Of California, Los Angeles;
- University Of California, Davis
Integrated Center For Structure And Function Innovation

Principal Investigator: Thomas C. Terwilliger, Los Alamos National Laboratory
Participating Institutions:
- Los Alamos National Laboratory;
- University of Chicago;
- University of Virginia;
- University of California, Los Angeles;
- Lawrence Livermore National Laboratory;
- Lawrence Berkeley National Laboratory
New York Consortium On Membrane Protein Structure
Principal Investigator: Wayne A. Hendrickson, New York Structural Biology Center
Participating Institutions:
- Columbia University,
- Albert Einstein College of Medicine,
- New York University,
- The Rockefeller University,
- SUNY Buffalo,
- University of Medicine
- Dentistry of New Jersey,
- Yale University

Homology Modeling centers

Joint Center For Molecular Modeling
New Methods For High-Resolution Comparative Modeling

Resource Centers

Two centers are being established to centralize resources developed by the PSI centers and increase the scientific community’s access to them.

Psi Materials Repository

Principal Investigator: Joshua LaBaer, Harvard Institute of Proteomics

Web site: http://www.hip.harvard.edu/

PSI Knowledgebase

The PSI Knowledgebase, still being planned by NIGMS, will serve as a headquarters for structural information generated by the PSI centers. For every protein, scientists will be able to find the best available information about its structure, biological function, and experimental determination. Scientists will be able to submit requests for protein structures they’d like the PSI to determine.

Centers
NIGMS supports the following research centers in its protein structure initiative. brief summaries of the centers are available below.
Large-Scale Centers Joint Center For Structural Genomics Principal Investigator: Ian Wilson, Scripps Research Institute Participating Institutions: The Scripps Research Institute, The University Of California At San Diego, The Burnham Institute, Stanford Synchrotron Radiation Laboratory, The Genomics Institute of the Novartis Research Foundation Midwest Center For Structural Genomics Principal Investigator: Andrzej Joachimiak, Argonne National Laboratory Participating Institutions: Argonne National Laboratory, European Bioinformatics Institute, University College London, The University Of Toronto New York Structural Genomix Research Consortium Principal Investigator: Stephen K. Burley, SGX Pharmaceuticals Inc., San Diego, Calif. Participating Institutions: Sgx Pharmaceuaticals Inc., Albert Einstein College Of Medicine, Brookhaven National Laboratory, Case Western Reserve University, University Of California, San Francisco Northeast Structural Genomics Consortium Principal Investigator: Gaetano Montelione, Rutgers University Participating Institutions: Columbia University, Hauptman Woodward Medical Research Institute, Ontario Cancer Institute At The University Of Toronto, Pacific Northwest National Laboratories, Rutgers University, Robert Wood Johnson Medical School At The Umdnj, Weill Medical School At Cornell University And Yale University
Specialized Centers Accelerated Technologies Center For Gene To 3d Structure Principal Investigator: Lance J. Stewart, Decode Biostructures Participating Institutions: Decode Biostructures; The Scripps Research Institute; University Of Chicago; Lyncean Technologies, Inc.; Micronics, Inc. Center For Eukaryotic Structural Genomics Principal Investigator: John L. Markley, University Of Wisconsin, Madison Participating Institutions: University Of Wisconsin, Madison; Medical College Of Wisconsin Center For High-Throughput Structural Biology Principal Investigator: George T. De Titta, Hauptman-Woodward Medical Research Institute Participating Institutions: Hauptman-Woodward Medical Research Institute, University Of Rochester, Cornell University, Stanford Synchrotron Light Source, University Of Pittsburgh, University Of Washington At Seattle The University Of Toronto Center For Structures Of Membrane Proteins Principal Investigator: Robert M. Stroud, University Of California, San Francisco Participating Institutions: University Of California, San Francisco; The Salk Institute; Advanced Light Source (als) Lawrence Berkeley National Laboratory; University Of California, Los Angeles; University Of California, Davis Integrated Center For Structure And Function Innovation Principal Investigator: Thomas C. Terwilliger, Los Alamos National Laboratory Participating Institutions: Los Alamos National Laboratory; University of Chicago; University of Virginia; University of California, Los Angeles; Lawrence Livermore National Laboratory; Lawrence Berkeley National Laboratory New York Consortium On Membrane Protein Structure Principal Investigator: Wayne A. Hendrickson, New York Structural Biology Center Participating Institutions: Columbia University, Albert Einstein College of Medicine, New York University, The Rockefeller University, SUNY Buffalo, University of Medicine Dentistry of New Jersey, Yale University
Homology Modeling centers Joint Center For Molecular Modeling New Methods For High-Resolution Comparative Modeling
Resource Centers Two centers are being established to centralize resources developed by the PSI centers and increase the scientific community’s access to them. Psi Materials Repository Principal Investigator: Joshua LaBaer, Harvard Institute of Proteomics Web site: http://www.hip.harvard.edu/ PSI Knowledgebase The PSI Knowledgebase, still being planned by NIGMS, will serve as a headquarters for structural information generated by the PSI centers. For every protein, scientists will be able to find the best available information about its structure, biological function, and experimental determination. Scientists will be able to submit requests for protein structures they’d like the PSI to determine.